CONFERENCE & EXHIBITION
HPC, AI, Quantum: Powering Innovation and Sustainability
ISC 2025 is the 40th anniversary of the world’s leading forum for advancing the application of high performance computing in academia, government, and the private sector. The goal of this annual event is to foster a global exchange of knowledge, innovation, and collaboration in the field.
ISC connects scientists, engineers, and technology leaders to explore the future of high performance computing. We will examine today’s breakthroughs in artificial intelligence, high performance computing and quantum technologies, as well as what lies ahead.
Additionally, we are committed to sustainability by promoting energy-efficient and cost-effective computing, while empowering the next-generation workforce to continue the community’s legacy of innovation.
ISC 2026 Dates
We are happy to announce that ISC will return to Hamburg from June 22–26, 2026!
- Tutorials: Monday, June 22
- Conference and Exhibition: Tuesday – Thursday, June, 23-25
- Workshops: Friday, June, 26
LOOKING AHEAD TO ISC 2027
Our mission to connect the dots will continue into 2027!
ISC will return to Hamburg during the week of June 7–11, 2027.
THEME:
CONNECTING THE DOTS
ISC brings together a mix of people from different backgrounds and areas of expertise to drive HPC. Whether you are just entering the field, in a mid-level position, a part of senior management, or a student, we welcome you to join our efforts to connect people and technologies.
READ MORE
High performance computing (HPC) has made significant strides over the last half-century, transitioning from the megascale era of the 1970s to the current exascale era. Over the past few decades, this technology has supported an array of increasingly computationally intensive applications in science, engineering, and business.
Today, artificial intelligence (AI) is advancing at an even faster pace than HPC. Still, it depends on the massive computational power and data throughput capabilities of high performance hardware to build and run its applications.
At the same time, quantum computing is emerging as a new and groundbreaking paradigm. While it differs from classical computing, many quantum applications are closely aligned with existing HPC workloads that could be significantly accelerated under this new paradigm. Likewise, combining quantum computing with AI has the potential to accelerate the training of AI models and data analysis.
The synergy that could result from merging HPC, AI, and quantum computing is an exciting prospect. And given the insatiable demand for performance to accelerate scientific discoveries and commercial applications, integrating these technologies is not just an academic goal, but an economic imperative.
With that in mind, we invite the community of research and commercial users, system developers, and service providers to join the journey of connecting the dots.
2027 PROGRAM CHAIR & DEPUTY CHAIR
“Our field is evolving fast – simulation, AI, data analytics, and new computing paradigms are converging in ways that are reshaping science itself. I want ISC 2027 to honor this moment: a program that is technically rigorous, but above all, a place where people from around the world come together to share, challenge, and inspire each other.” Rio Yokota
RIO YOKOTA
Professor, Supercomputing Research Center, Institute of Integrated Research, Institute of Science Tokyo, Japan
AMANDA RANDLES
Associate Professor of Biomedical Sciences and Biomedical Engineering at Duke University, USA
ABOUT RIO YOKOTA
Rio Yokota is a Professor at the Supercomputing Research Center, Institute of Integrated Research, Institute of Science Tokyo. He also leads the AI for Science Foundation Model Research Team at RIKEN Center for Computational Science. His research interests lie at the intersection of high performance computing, machine learning, and linear algebra. He has been optimizing algorithms on GPUs since 2007, and was part of a team that received the Gordon Bell prize in 2009 using the first GPU supercomputer. More recently, he has been leading distributed training efforts on Japanese supercomputers such as ABCI, TSUBAME, and Fugaku. He is the co-developer of the Japanese LLM Swallow, and LLM-jp. He is also involved in the organization of multinational collaborations such as ADAC and TPC.
ABOUT AMANDA RANDLES
Amanda Randles is the Alfred Winborne Mordecai and Victoria Stover Mordecai Associate Professor of Biomedical Sciences and Biomedical Engineering at Duke University, where she also serves as Director of the Duke Center for Computational and Digital Health Innovation. Her research focuses on the development of patient-specific digital twin models that integrate high performance computing, machine learning, and multiscale biophysical simulations to enable proactive diagnosis and treatment of diseases ranging from cardiovascular disease to cancer. Her contributions have been recognized with the ACM Prize in Computing, the NIH Pioneer Award, the NSF CAREER Award, the ACM Grace Hopper Award, the Jack Dongarra Early Career Award, and the Sony and Nature Women in Technology Award. Randles received her Ph.D. in Applied Physics from Harvard University, an M.S. in Computer Science from Harvard, and a B.A. in Computer Science and Physics from Duke. Prior to graduate school, she worked as a software engineer at IBM on the Blue Gene supercomputing team.
News
FOR EXHIBITS
Scientists, researchers, and engineers of all career levels are invited to contribute to the program. Their submissions will have an impact on the conference program.
FOR EXHIBITS
Scientists, researchers, and engineers of all career levels are invited to contribute to the program. Their submissions will have an impact on the conference program.
FOR EXHIBITS
Scientists, researchers, and engineers of all career levels are invited to contribute to the program. Their submissions will have an impact on the conference program.
ISC 2026 Concludes with Record Attendees and TOP500 Moves to ACM
ISC Introduces Rio Yokota as ISC 2027 Program Chair
ISC 2026 Gears Up for an Exciting Finale!
A UNIQUE EVENT!
The elements that set ISC apart from other events in the industry:
EUROPE'S LARGEST HPC EXHIBITION
FUTURE-PROOF TECHNICAL PROGRAM
800+ SPEAKERS @ ALL CAREER LEVELS
NETWORKING & SOCIAL ACTIVITIES
CONNECTING COMMUNITIES & TECHNOLOGIES
ENGAGING THE NEXT GENERATION
MISSED ISC 2026?
Catch up on the latest trends in HPC, AI, and quantum computing from Hamburg from free. Read our AI summaries for quick insights, or register for On-Demand Content to unlock full access to all keynotes and panels until the end of 2026.
You are currently viewing a placeholder content from YouTube. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.
More Information2026 KEYNOTE SPEAKERS

OPENING KEYNOTE
MARTIN SCHULZ
Professor in Computer Engineering, TUM & Member of the Board of Directors at LRZ, Germany
THE ISC EXHIBITION
The ISC Exhibition brings together over 200 leading organizations from industry, research, and academia, offering a unique picture of the converging ecosystems of HPC, AI, and quantum technologies.
It is where ideas, expertise, and partnerships come together – enabling meaningful connections across the community.
To participate as an exhibitor or sponsor, please express your interest, and we will get in touch with you.
EVENT PARTNER
On September 22–23, 2026, Bitkom’s AI, Data and Quantum Summit (AIDAQ) will bring together more than 2,500 experts in Berlin to discuss the future of artificial intelligence, the data economy, and quantum computing. Attendees can look forward to more than 200 distinguished speakers from politics, business, and academia, as well as a wide range of networking and professional development opportunities on site. Get your ticket now and save 20% with the discount code AIDAQ_ISC20!
DOORS OPEN IN
You are currently viewing a placeholder content from YouTube. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.
More InformationJOIN THE GLOBAL HPC COMMUNITY!
ISC 2025 unites over 3,000 technology developers, providers and users to foster a strong community. Join now and take advantage of early bird pricing!
ISC 2025 unites over 3,500 technology developers, providers and users to foster a strong community.
UPCOMING SUBMISSION DEADLINES
DECEMBER 19, 2025
Jan 22, 2026 JAN 29, 2026
JANUARY 28, 2026
it's a wrap!
ISC 2026 KEYNOTE SPEAKERS

OPENING KEYNOTE
MARTIN SCHULZ
Professor in Computer Engineering, TUM & Member of the Board of Directors at LRZ, Germany
→ View Abstract & Speaker Bio

MIDWEEK KEYNOTE
AMANDA RANDLES
Associate Professor of Biomedical Sciences and Biomedical Engineering at Duke University
→ View Abstract & Speaker Bio

CLOSING KEYNOTE
JACK DONGARRA
Research Professor Emeritus, University of Tennessee & Distinguished Research Staff Member, ORNL, USA
→ View Abstract & Speaker Bio
FIVE DAYS OF WHAT MOVES HPC FORWARD.
From in-depth tutorials and expert-led workshops to keynotes, networking opportunities, and Europe’s premier HPC exhibition – five days dedicated to HPC, AI, and quantum computing in Hamburg.
INVITED PROGRAM SPEAKER SPOTLIGHTS
Discover selected experts contributing to the ISC Invited Program.
HELP SHAPE THE INVITED PROGRAM!
Share your nominations for speakers, panelists and chairs, especially talented early-career individuals, including women and researchers from underrepresented regions, who deserve to be recognized on a global stage.
join as a contributor now!
UPCOMING SUBMISSION DEADLINES
DECEMBER 19, 2025
Jan 22, 2026 JAN 29, 2026
JANUARY 28, 2026
Be part of ISC 2026 CONTRIBUTED program!
| Submission Deadlines | Notification of Acceptance | |
|---|---|---|
| Workshops with proceedings | October 20, 2025 | December 5, 2025 |
| Regular Workshops | December 10, 2025 | February 4, 2026 |
| Tutorials | December 11, 2025 | February 10, 2026 |
| Research Paper |
December 12, 2025 (Abstract Submission Deadline) December 19, 2025 (Full Submission Deadline / no extension) |
March 18, 2026 |
| Research Poster | January 22, 2026 | March 3, 2026 |
| Project Poster | January 22, 2026 | March 3, 2026 |
| Birds of a Feather | January 28, 2026 | March 5, 2026 |
EXHIBIT AT ISC 2026
Meet over 3,500 international attendees across HPC, AI, and quantum computing. Showcase your solutions, build partnerships, and generate qualified leads.
To participate as an exhibitor or sponsor, please express your interest, and we will get in touch with you.
ISC 2025 SPONSORS
A UNIQUE EVENT
The elements that set ISC apart from other events in the industry:
Comprehensive Program Addressing HPC and AI Innovation
Stay ahead in the industry by engaging with a program that highlights cutting-edge innovations and discusses key issues that are shaping the future of high performance computing.
Networking Opportunities & Social Activities
Engage with as many attendees as possible during the event and through curated social activities. Nearly 50% of HPC users, vendors, and providers participate exclusively at ISC.
Insights From 750+ Speakers
Gain valuable insights from scientists, researchers, and engineers across all career levels, geographies, and research domains.
Bridging Technology and Community
Foster collaboration across technologies and communities. ISC offers engaging formats and unique sessions that cater to a diverse audience with varied perspectives.
Europe’s Largest HPC Exhibition
Explore the latest breakthroughs in HPC, AI, and quantum computing, all brought to the show floor by 160 vendors, public institutions, and startups.