Contributor Index

Dr. Macklin is an Associate Professor and Director of Undergraduate Studies in the Department of Intelligent Systems Engineering at Indiana University in the United States. His lab develops open source computational tools for multicellular systems biology. He has developed cross-platform, parallelized C++ open source codes for multi-substrate diffusion (BioFVM) and large-scale agent-based simulations in 3-D tissues (PhysiCell). These codes have been applied to diverse problems in cancer biology, nanotherapy, tissue engineering, immunology, cryobiology, synthetic systems, and microbiology. He has worked closely with others to develop new capabilities for the PhysiCell platform, such as integrated Boolean signaling networks (PhysiBoSS), high-throughput model exploration and optimization on supercomputer resources (PhysiCell-EMEWS), and cloud deployment of user-interactive agent-based models (such as pc4cancerimmune, hosted via nanoHUB).